For such long distances, travelling by bus could not be the best solution. Check out alternatives by plane: with some luck, you will find low-cost tickets from Ghent to Bolzano and be a lot faster!
How many bus connections exist to go from Ghent to Bolzano per day?
When do the first and last buses from Ghent to Bolzano leave?
While the first bus leaves at 12:06, the last one leaves Ghent at 21:06. The duration of the journey is on average 19 hours and 50 minutes, but it can take you only 18 hours and 5 minutes with the fastest connections.
Which bus companies serve the route Ghent - Bolzano?
There are many companies cooperating with virail, among which also FlixBus with buses to Bolzano.
Flixbus is undoubtedly one of the youngest and most famous bus companies in whole Europe. With more than 40 millions passengers only in 2017, Flixbus offers national and international bus connections, also with night buses.